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Phenotype Image Detail
Image
Caption Preaxial polydactyly and blood-filled blisters in the hindlimbs of Fras1bfb/Fras1bfb mice. Blood-filled blisters are evident in the hindlimbs of mutants at E14.5 (A and B) and E17.5 (C and D), often distorting the digits. A proportion of mutants exhibit preaxial polydactyly (asterisks in E-H), evident in E14.5 and E17.5 wholemounts (E and F), E17.5 skeletal preparations (G) and E12.5 Sox9 in situ stained embryos (H). Evidence of a blister can also be seen in an E17.5 skeletal preparation (arrowhead in G). Digit numbers are indicated in (G).
Copyright This image is from Miller KA, PLoS One 2013;8(10):e76342, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:208682
Associated
Alleles
Symbol Name
Fras1bfb Fraser extracellular matrix complex subunit 1; blood filled blisters
Associated
Genotypes
Allelic Composition Genetic Background
Fras1bfb/Fras1bfb involves: C57BL/6JAnu

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory