Phenotype Image Detail

Image

Caption

Representative images of testis sections stained with Haematoxylin and eosin (left panels) and ApopTag for the detection of apoptotic cells (right panels). Note the multinucleated giant cells (black arrow) frequently present in the lumen in the testes from Nabp2^tm1.1Kkha/Nabp2^tm1.1Kkha Gt(ROSA)26Sor^{tm9(cre/ESR1)Arte}/Gt(ROSA)26Sor⁺ (Ssb1^-/-) mice. Spermatogenic cells in mutant testes showed an elevated apoptotic marker (black arrows, lower panel, right, Scale = 25 mm).

Copyright

This image is from Shi W, PLoS Genet 2013 Feb;9(2):e1003298, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195140

Associated Alleles

Symbol	Name
Gt(ROSA)26Sor^tm9(cre/ESR1)Arte	gene trap ROSA 26, Philippe Soriano; targeted mutation 9, TaconicArtemis
Nabp2^tm1.1Kkha	nucleic acid binding protein 2; targeted mutation 1.1, Kum Kum Khanna

Associated Genotypes

Allelic Composition	Genetic Background
Nabp2^tm1.1Kkha/Nabp2^tm1.1Kkha Gt(ROSA)26Sor^tm9(cre/ESR1)Arte/Gt(ROSA)26Sor^+	involves: C57BL/6 * C57BL/6NTac