Phenotype Image Detail

Image

Caption

Images (J,L) and histologic sections (K,M) of E10.5 embryos generated with Tg(Nkx2-5-cre)9Eno, which is specific for early embryonic myocardium (J-M). (L,M) Growth retardation and myocardial thinning are seen in Gata4^tm1.1Wtp/Gata4^tm1Grg Tg(Nkx2-5-cre)9Eno/0 (Gata4^flox/G295S;Nkx2-5-Cre+) mice. A, atria; V, ventricle; scale bars indicate 200 um.

Copyright

This image is from Misra C, PLoS Genet 2012 May;8(5):e1002690, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:185124

Associated Alleles

Symbol	Name
Gata4^tm1.1Wtp	GATA binding protein 4; targeted mutation 1.1, William T Pu
Gata4^tm1Grg	GATA binding protein 4; targeted mutation 1, Vidu Garg
Tg(Nkx2-5-cre)9Eno	transgene insertion 9, Eric N Olson

Associated Genotypes

Allelic Composition	Genetic Background
Gata4^tm1Grg/Gata4^tm1.1Wtp Tg(Nkx2-5-cre)9Eno/0	involves: 129 * C57BL/6