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Phenotype Image Detail
Image
Caption Ablation of medium-spiny projection neurons in the striatum of Gng7tm2(cre/PGR)Mmsh/Gng7+ Eno2tm1(DTA)Hsak/Eno2+ (mutant) mice. A, Immunoreactivity for calbindin in the dorsal striatum of control (upper) and Gng7tm2(cre/PGR)Mmsh/Gng7+ Eno2tm1(DTA)Hsak/Eno2+ (lower) mice. B, Immunoreactivity for tyrosine hydroxylase and substance P in substantia nigra of control and mutant mice. Abbreviations: CP, caudate putamen; GP, globus pallidus; SNc, substantia nigra pars compacta; SNr, substantia nigra pars reticulata; VTA, ventral tegmental area. Scale bars, 1 mm.
Copyright This image is from Kishioka A, PLoS ONE 2009;4(1):e4157, an open-access article distributed under the terms of the Creative Commons Attribution License. J:145152
Associated
Alleles
Symbol Name
Eno2tm1(DTA)Hsak enolase 2, gamma neuronal; targeted mutation 1, Hitoshi Sakno
Gng7tm2(cre/PGR)Mmsh guanine nucleotide binding protein (G protein), gamma 7; targeted mutation 2, Masayoshi Mishina
Associated
Genotypes
Allelic Composition Genetic Background
Eno2tm1(DTA)Hsak/Eno2+
Gng7tm2(cre/PGR)Mmsh/Gng7+
involves: C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory