Phenotype Image Detail

Image

Caption

(F) Transmission electron microscopy of ultrathin sections from distal sciatic nerve stumps 14 days after nerve crush injury in Col1a1^{tm1(CAG-Sirt2)Jmi}/Col1a1^{tm1(CAG-Sirt2)Jmi} Tg(Mpz-cre)26Mes/0 (Sirt2-SCTG) and Col1a1^{tm1(CAG-Sirt2)Jmi} control mouse. Arrows point to regenerated fibers. Note thinner compact myelin sheaths around axons from the Sirt2-SCTG preparation. (Scale bar: 2 um.)

Copyright

This image is from Beirowski B, Proc Natl Acad Sci U S A 2011 Oct 25;108(43):E952-61. Copyright 2011 National Academy of Sciences, U.S.A. J:177468

Associated Alleles

Symbol	Name
Col1a1^tm1(CAG-Sirt2)Jmi	collagen, type I, alpha 1; targeted mutation 1, Jeffrey Milbrandt
Tg(Mpz-cre)26Mes	transgene insertion 26, Albee Messing

Associated Genotypes

Allelic Composition	Genetic Background
Col1a1^tm1(CAG-Sirt2)Jmi/Col1a1^+ Tg(Mpz-cre)26Mes/0	involves: 129S4/SvJae * C57BL/6 * FVB/N