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Phenotype Image Detail
Image
Caption (C) Comparison of liver histopathology of Listeria monocytogenes (Lm) infected mice. Representative parenchyma (Upper) and perivascular (Lower) images from H&E stained wild-type (BL6) livers infected with 5 x 103 Lm compared with Trpm2tm1.1Alp/Trpm2tm1.1Alp (TRPM2-/-) and Ifngr1tm1Agt/Ifngr1tm1Agt (IFNgammaR-/-) moribund mice. Original magnification 200x; dotted lines outline areas of necrosis; asterisks denote blood vessel.
Copyright This image is from Knowles H, Proc Natl Acad Sci U S A 2011 Jul 12;108(28):11578-83. Copyright 2011 National Academy of Sciences, U.S.A. J:174397
Associated
Alleles
Symbol Name
Ifngr1tm1Agt interferon gamma receptor 1; targeted mutation 1, Michel Aguet
Trpm2tm1.1Alp transient receptor potential cation channel, subfamily M, member 2; targeted mutation 1.1, Anne-Laure Perraud
Associated
Genotypes
Allelic Composition Genetic Background
Ifngr1tm1Agt/Ifngr1tm1Agt involves: 129S7/SvEvBrd
Trpm2tm1.1Alp/Trpm2tm1.1Alp B6.129P2-Trpm2tm1.1Alp

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory