Phenotype Image Detail

Image

Caption

(C) Comparison of liver histopathology of Listeria monocytogenes (Lm) infected mice. Representative parenchyma (Upper) and perivascular (Lower) images from H&E stained wild-type (BL6) livers infected with 5 x 10³ Lm compared with Trpm2^tm1.1Alp/Trpm2^tm1.1Alp (TRPM2-/-) and Ifngr1^tm1Agt/Ifngr1^tm1Agt (IFNgammaR-/-) moribund mice. Original magnification 200x; dotted lines outline areas of necrosis; asterisks denote blood vessel.

Copyright

This image is from Knowles H, Proc Natl Acad Sci U S A 2011 Jul 12;108(28):11578-83. Copyright 2011 National Academy of Sciences, U.S.A. J:174397

Associated Alleles

Symbol	Name
Ifngr1^tm1Agt	interferon gamma receptor 1; targeted mutation 1, Michel Aguet
Trpm2^tm1.1Alp	transient receptor potential cation channel, subfamily M, member 2; targeted mutation 1.1, Anne-Laure Perraud

Associated Genotypes

Allelic Composition	Genetic Background
Ifngr1^tm1Agt/Ifngr1^tm1Agt	involves: 129S7/SvEvBrd
Trpm2^tm1.1Alp/Trpm2^tm1.1Alp	B6.129P2-Trpm2^tm1.1Alp