About   Help   FAQ
Phenotype Image Detail
Image
Caption (N-P) Terttm1Leah/Terttm1Leah (TERT) knockout prevents telomere elongation in Pinx1tm1.1Kplu/Pinx1+ MEFs at late passage, as determined by qFISH. (P) Terttm1Leah/Terttm1Leah knockout prevents anaphase brides and/or lagging chromosomes in Pinx1tm1.1Kplu/Pinx1+ MEFs at late passage.
Copyright This image is from Zhou XZ, J Clin Invest 2011 Apr 1;121(4):1266-82 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:171997
Associated
Alleles
Symbol Name
Pinx1tm1.1Kplu PIN2/TERF1 interacting, telomerase inhibitor 1; targeted mutation 1.1, Kun Ping Lu
Terttm1Leah telomerase reverse transcriptase; targeted mutation 1, Lea Harrington
Associated
Genotypes
Allelic Composition Genetic Background
Pinx1tm1.1Kplu/Pinx1+
Terttm1Leah/Terttm1Leah
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * FVB/N

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/26/2014
MGI 5.19
The Jackson Laboratory