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Phenotype Image Detail
Image
Caption Phenotype of Myh11tm2Peri/Myh11tm2Peri mice. (A) (Upper) Comparison of bladder (square 1), alimentary tract (square 2) including stomach (square 3), and the kidney (square 4) in wild-type (SM2+/+) and Myh11tm2Peri/Myh11tm2Peri (SM2-/-) mice (20 days). Note the retention of urine in the renal pelvis of the mutant kidney. (Lower) Development end-stage hydronephrosis with severe retention of urine in the renal pelvis in 25-day mutant mice and kidneys in age-matched wild-type mice. (B) (Upper) Comparison of neonatal and peri-mortal mutant with age-matched wild-type bladders. (Lower) Histology (40x) of peri-mortal mutant and age-matched wild-type bladders.
Copyright This image is from Chi M, Proc Natl Acad Sci U S A 2008 Nov 25;105(47):18614-8. Copyright 2008 National Academy of Sciences, U.S.A. J:142230
Associated
Alleles
Symbol Name
Myh11tm2Peri myosin, heavy polypeptide 11, smooth muscle; targeted mutation 2, Muthu Periasamy
Associated
Genotypes
Allelic Composition Genetic Background
Myh11tm2Peri/Myh11tm2Peri involves: 129 * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory