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Phenotype Image Detail
Image
Caption Characterization of the developmental defects of the Pdgfctm1.1Hdin/Pdgfctm1.1Hdin embryos. (B) A coronal section of E15.5 wild-type embryo shows the fusion of palate shelves. (C) On the contrary, the Pdgfctm1.1Hdin/Pdgfctm1.1Hdin embryo developed cleft palate as two palate shelves (PS) did not fuse at the midline at E15.5. In addition, these mutant embryos also had the formation of subepithelial blister in the nasal septum (arrow indicated).
Copyright This image is from Wu X, Genesis 2007 Oct;45(10):653-7, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:128709
Associated
Alleles
Symbol Name
Pdgfctm1.1Hdin platelet-derived growth factor, C polypeptide; targeted mutation 1.1, Hao Ding
Associated
Genotypes
Allelic Composition Genetic Background
Pdgfctm1.1Hdin/Pdgfctm1.1Hdin involves: 129 * C57BL/6 * FVB/N * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory