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Phenotype Image Detail
Image
Caption Appearance of wild-type (Lats2+/+), Lats2tm1Noj/Lats2+ (Lats2+/-), and Lats2tm1Noj/Lats2tm1Noj (Lats2-/-) mouse embryos at different stages during embryonic development. A-C, at E10.5, morphology of the homozygous mutant embryo was relatively normal, although body size was smaller than those of wild-type and heterozygous embryos. D-I, at E11.5 and E12.5, mutant embryos were severely growth-retarded. J-L, at E13.5, mutant embryo shows abnormal gross morphology and death.
Copyright This image is from Yabuta N, J Biol Chem 2007 Jun 29;282(26):19259-71 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:123480
Associated
Alleles
Symbol Name
Lats2tm1Noj large tumor suppressor 2; targeted mutation 1, Hiroshi Nojima
Associated
Genotypes
Allelic Composition Genetic Background
Lats2tm1Noj/Lats2tm1Noj involves: 129S2/SvPas * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory