Phenotype Image Detail

Image

Caption

Electron microscopic analysis of spinal anterior horn regions. A and B: Electron micrographs of cross sections of the anterior horn regions of the spinal cords (thoracic level 7, T7) of wild-type (A) and Kif1a^tm1Noh/Kif1a^tm1Noh (B) mice. The densities of nerve terminals and synaptic vesicles were decreased in the mutant mice. Arrows indicate nerve terminals. C and D: Nerve terminals of wild-type (C) and mutant (D) mice. G and H: Neuronal cell bodies in the wild-type (G) and mutant mice (H). Neuronal cell bodies containing clusters of small vesicles were observed in the mutant mice (H) but not the wild-type mice (G). Arrows, clusters of small vesicles (H). I: A higher-magnification view of one of these clusters. ga, the Golgi apparatus. Bars: (A and B) 1.4 um; (C and D) 400 nm; (G and H) 2 um; (I) 400 nm.

Copyright

This image is from Yonekawa Y, J Cell Biol 1998 Apr 20;141(2):431-41, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:47170

Associated Alleles

Symbol	Name
Kif1a^tm1Noh	kinesin family member 1A; targeted mutation 1, Nobutaka Hirokawa

Associated Genotypes

Allelic Composition	Genetic Background
Kif1a^tm1Noh/Kif1a^tm1Noh	involves: 129S4/SvJae * C57BL/6