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Phenotype Image Detail
Caption Phenotype of HrHp/HrHp mice. A: Hair loss and skin folds of 7 and 12 day old wild-type (+/+), HrHp/Hr+ (HrHp/+) and HrHp/HrHp mice. Heterozygous mice had the reduced number of hairs. Homozygous mice had wrinkled skin and no hair. B: Histological features of wild-type, heterozygous and homozygous mice at P7 to P210. Homozygous mice showed abnormal hair follicle (HF) formationas early as P7, with small HFs and canals that did not penetrate the epidermis; these HF became eosinophilic cyst-like structures by P21. The HF morphology of the heterozygous mice was similar to that of wild-type littermates. HFs in heterozygous mice exhibited normal cycling. At an older age (P210), heterozygous mice displayed follicular cyst-like structure (arrowhead) and bent yet normal HFs (arrow), while wild-type mice had normal HFs. The skin of homozygotes was filled with cysts only. Scale bar = 50um.
Copyright This image is from Baek IC, Mamm Genome 2009 Jun;20(6):350-8 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:150720
Symbol Name
HrHp hairless; hairpoor
Allelic Composition Genetic Background
HrHp/HrHp BALB/cJ-HrHp
HrHp/Hr+ BALB/cJ-HrHp

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