Phenotype Image Detail

Image

Caption

A-C: Hands in human recessive dystrophic epidermolysis bullosa (RDEB) patients at 2.5 years (A), 6.5 years (B), and 7.5 years of age (C). D-G: Fore paws of Col7a1^tm1Lbt/Col7a1^tm1Lbt mice were documented at 17 days (D), 60 days (E), and 80 days of age (F and G). The clinical pehnotypes in RDEB patients and in mutant mice developed in a similar manner.

Copyright

This image is from Fritsch A, J Clin Invest 2008 May;118(5):1669-79 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:136145

Associated Alleles

Symbol	Name
Col7a1^tm1Lbt	collagen, type VII, alpha 1; targeted mutation 1, Leena Bruckner-Tuderman

Associated Genotypes

Allelic Composition	Genetic Background
Col7a1^tm1Lbt/Col7a1^tm1Lbt	involves: 129S1/Sv * 129X1/SvJ * C57BL/6Crl