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Phenotype Image Detail
Image
Caption Gross analysis of newborn wild-type and Slc27a4tm1Wsr/Slc27a4tm1Wsr littermates. A-C: Gross morphology of wild-type (Fatp4 +/+) and Slc27a4tm1Wsr/Slc27a4tm1Wsr (Fatp4 -/-) neonates. At birth, mutant progeny were smaller and had a markedly abnormal appearance with facial dysmorphis, a compressed torso, and a taut skin exhibiting a scaly, wrinkle-free surface and extending over and covering the proximal extremities, the joints of which were fixed in flexion contracture. D: Alcian blue/Alizarin red S staining of wild-type and mutant skeletons revealed no gross morphological differences, neither in bone nor in cartilage. The flexion joint contractures persisted after the staining procedure.
Copyright This image is from Herrmann T, J Cell Biol 2003 Jun 23;161(6):1105-15, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:84096
Associated
Alleles
Symbol Name
Slc27a4tm1Wsr solute carrier family 27 (fatty acid transporter), member 4; targeted mutation 1, Wolfgang Stremmel
Associated
Genotypes
Allelic Composition Genetic Background
Slc27a4tm1Wsr/Slc27a4tm1Wsr involves: 129P2/OlaHsd * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory