About   Help   FAQ
Phenotype Image Detail
Image
Caption Skull development in Gja1tm1Kdr/Gja1tm1Kdr embryos. A and B: Lateral view of the skull of alizarin red/alcian blue-stained E16.5 wild-type (WT) and Gja1tm1Kdr/Gja1tm1Kdr (Cx43(-/-)) embryos. C and D: Dorsal, E and F: ventral, and G and H: lateral views of the skull of alizarin red-stained E18.5 (C,E and G) wild-type and (D,F and H) mutant embryos. G and H: Lateral view on the skull at E18.5 shows the incipient mineralization of parietal, nasal, frontal and squamous parts of the temporal bones in mutant mice, though all these elements remain developmentally hypomineralized, especially around their rostral boundaries. F, frontal bone; P, parietal bone; S, squamous part of the temporal bone; I, interparietal bone; E, exoccipital bone; M, mandible; T, tympanic ring; PL, palatine bone; PT, pterygoid bone; BS, basisphenoid bone; AS, alisphnoid bone; and BO, basioccipital bone.
Copyright This image is from Lecanda F, J Cell Biol 2000 Nov 13;151(4):931-44, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:65866
Associated
Alleles
Symbol Name
Gja1tm1Kdr gap junction protein, alpha 1; targeted mutation 1, Gerald M Kidder
Associated
Genotypes
Allelic Composition Genetic Background
Gja1tm1Kdr/Gja1tm1Kdr involves: 129S1/Sv * 129X1/SvJ * C57BL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory