Phenotype Image Detail

Image

Caption

Med1^tm1Jkr/Med1^tm1Jkr (PBP-/-, b,d and f) embryos exhibit pericardial effusion (arrow, b), hypoplastic myocardium (d), and endothelial cells (arrows, f) lifting off from underlying pyknotic myocytes as compared with wild-type (WT, a,c and e). V, ventricle. Sections c-f were stained with hematoxylin and eosin.

Copyright

This image is from Crawford SE, J Biol Chem 2002 Feb 1;277(5):3585-92 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:74328

Associated Alleles

Symbol	Name
Med1^tm1Jkr	mediator complex subunit 1; targeted mutation 1, Janardan K Reddy

Associated Genotypes

Allelic Composition	Genetic Background
Med1^tm1Jkr/Med1^tm1Jkr	involves: 129P2/OlaHsd * C57BL/6