Phenotype Image Detail

Image

Caption

A: Adipocyte morphology in eWAT and brown adipose tissue (BAT) of wild type (WT) and Pparg^tm1Lja/Pparg⁺ mice. Note the heterogeneity of cells in both adipose tissue depots of mutant mice. B: Summary of adipocyte number and size in eWAT. C: Real-time RT-PCR analysis of adipocyte-specific gene expression in eWAT. Data are expressed as relative expression of candidate genes in mutant mice versus wild type mice. D: Western blot analysis of PPARG and SREBP-1 protein expression in eWAT. The eWAT was harvested from five month old male mice.

Copyright

This image is from Freedman BD, J Biol Chem 2005 Apr 29;280(17):17118-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:98786

Associated Alleles

Symbol	Name
Pparg^tm1Lja	peroxisome proliferator activated receptor gamma; targeted mutation 1, J Larry Jameson

Associated Genotypes

Allelic Composition	Genetic Background
Pparg^tm1Lja/Pparg^+	involves: 129S1/Sv * 129X1/SvJ