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Phenotype Image Detail
Caption A: Adipocyte morphology in eWAT and brown adipose tissue (BAT) of wild type (WT) and Ppargtm1Lja/Pparg+ mice. Note the heterogeneity of cells in both adipose tissue depots of mutant mice. B: Summary of adipocyte number and size in eWAT. C: Real-time RT-PCR analysis of adipocyte-specific gene expression in eWAT. Data are expressed as relative expression of candidate genes in mutant mice versus wild type mice. D: Western blot analysis of PPARG and SREBP-1 protein expression in eWAT. The eWAT was harvested from five month old male mice.
Copyright This image is from Freedman BD, J Biol Chem 2005 Apr 29;280(17):17118-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:98786
Symbol Name
Ppargtm1Lja peroxisome proliferator activated receptor gamma; targeted mutation 1, J Larry Jameson
Allelic Composition Genetic Background
Ppargtm1Lja/Pparg+ involves: 129S1/Sv * 129X1/SvJ

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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