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Phenotype Image Detail
Image
Caption Hepatic lipid accumulation is observed in 5 month old male mice on a standard or high fat (HF) diet. A: Hematoxylin and eosin liver histology of wild type (WT) and Ppargtm1Lja/Pparg+ (KI) mice. Both macrovesicular and microvesicular fat depositions are observed in mutant mice on a HF diet. PV, peripheral vein; CV, central vein. B: Hepatic TG (triglyceride) content for wild type and mutant mice. The mean +/- standard deviation is presented for the four groups of 5 month old mal mice; n = 4 or 5 for each group.
Copyright This image is from Freedman BD, J Biol Chem 2005 Apr 29;280(17):17118-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:98786
Associated
Alleles
Symbol Name
Ppargtm1Lja peroxisome proliferator activated receptor gamma; targeted mutation 1, J Larry Jameson
Associated
Genotypes
Allelic Composition Genetic Background
Ppargtm1Lja/Pparg+ involves: 129S1/Sv * 129X1/SvJ

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory