Phenotype Image Detail

Image

Caption

Hematoxylin and eosin (a) and immunohistochemical staining with anti-fibrin(ogen) antibody (b) of the head of a Serpinc1^tm1Sai/Serpinc1^tm1Sai embryo at 16.5 gd. Extensive hemorrhage was observed subcutaneously and intracranially (a), but there was no apparent fibrin(ogen) deposition (b). Size bar, 100um.

Copyright

This image is from Ishiguro K, J Clin Invest 2000 Oct;106(7):873-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:65092

Associated Alleles

Symbol	Name
Serpinc1^tm1Sai	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1; targeted mutation 1, Hidehiko Saito

Associated Genotypes

Allelic Composition	Genetic Background
Serpinc1^tm1Sai/Serpinc1^tm1Sai	involves: 129S2/SvPas * C57BL/6J