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Phenotype Image Detail
Caption Microscopic observation of wild type (a and b) and Serpinc1tm1Sai/Serpinc1tm1Sai (c-f) embryos at 15.5 gd. a and c: Hematoxylin-eosin and (b and d) immunochemical staining with antifibrin(ogen) antibody. e and f: Magnification of the areas indicated in d. e: Myocardium. f: Liver. A mutant embryo at 15.5 gd showed degeneration of the myocardium and liver (c). Fibrin(ogen) deposition was observed in the myocardium and sinusoids of the liver (d, e and f). Size bars, 100um.
Copyright This image is from Ishiguro K, J Clin Invest 2000 Oct;106(7):873-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:65092
Symbol Name
Serpinc1tm1Sai serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1; targeted mutation 1, Hidehiko Saito
Allelic Composition Genetic Background
Serpinc1tm1Sai/Serpinc1tm1Sai involves: 129S2/SvPas * C57BL/6J

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