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Phenotype Image Detail
Image
Caption A: IgE and IgG levels in sera of nine controls (CT) and nine Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 (MT) mice at week 12. The average values are indicated by short lines. B: Lymph node (LN) hyperplasia and splenomegaly in MT mice. Cervical LNs and spleens from a CT and two MT (MT1 and MT2) mice are shown at week 20. The relative weights of cervical LN and spleen body weights (BW) from CT and MT mice at week 0-20 are presented. C: Luna's staining of cervical LN, spleen and liver sections (as indicated) at week 12. The white arrow points to one of the many eosinophils (stained red in cytoplasn and blue nucleus). The black arrowhead points to erythrocytes (stained red in cytoplasm). V, vein. Scale bar, 25um.
Copyright This image is from Li M, Proc Natl Acad Sci U S A 2005 Oct 11;102(41):14795-800. Copyright 2005 National Academy of Sciences, U.S.A. J:102470
Associated
Alleles
Symbol Name
Rxratm4Ipc retinoid X receptor alpha; targeted mutation 4, Pierre Chambon
Rxrbtm1Pcn retinoid X receptor beta; targeted mutation 1, Pierre Chambon
Tg(KRT14-cre/ERT2)1Ipc transgene insertion 1, I Pierre Chambon
Associated
Genotypes
Allelic Composition Genetic Background
Rxratm4Ipc/Rxratm4Ipc
Rxrbtm1Pcn/Rxrbtm1Pcn
Tg(KRT14-cre/ERT2)1Ipc/0
involves: 129S2/SvPas

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory