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Phenotype Image Detail
Caption A-F: Immunohistochemical (IHC) staining was performed on ear sections from control (CT) and Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 (MT) mice at week 8, with antibodies against CD4 (A and B), CD11c (C and D), and MHCII (E and F). Red color corresponds to staining of antibodies, whereas blue corresponds to DAPI staining of nuclei. White arrows point to dermal/epidermal junction. Scale bar 50um. G-H: Luna's staining. Eosinophils (pointed by red arrows in H, Inset) display intracytoplasmic red staining. I-J: Electron microscopic (EM) analyses. Eosinophils with crystal-like rectangular inclusions are pointed by blcak arrows and shown enlarged in J, inset. K-L: Toluidin blue-stained sections. In each panel, the black arrow points to one of the mast cells showing intensive blue color. Scale bars, G, H, K and L, 50um; I and J, 2um.
Copyright This image is from Li M, Proc Natl Acad Sci U S A 2005 Oct 11;102(41):14795-800. Copyright 2005 National Academy of Sciences, U.S.A. J:102470
Symbol Name
Rxratm4Ipc retinoid X receptor alpha; targeted mutation 4, Pierre Chambon
Rxrbtm1Pcn retinoid X receptor beta; targeted mutation 1, Pierre Chambon
Tg(KRT14-cre/ERT2)1Ipc transgene insertion 1, I Pierre Chambon
Allelic Composition Genetic Background
involves: 129S2/SvPas

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