Phenotype Image Detail

Image

Caption

Hematoxylin and eosin stained sections from representative time points of wild type and Mif^tm1Dvd/Mif^tm1Dvd mice treated with N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN). Arrows denote; subepithelial inflammation (4 week) and squamous metaplasia (8 week). High grade carcinoma is present at 20 weeks. Arrowheads show muscle cells with (wild type) and without (mutant) invasive carcinoma.

Copyright

This image is from Taylor JA rd, BMC Cancer 2007;7():135, an open-access article, licensee BioMed Central Ltd. J:126543

Associated Alleles

Symbol	Name
Mif^tm1Dvd	macrophage migration inhibitory factor (glycosylation-inhibiting factor); targeted mutation 1, John R David

Associated Genotypes

Allelic Composition	Genetic Background
Mif^tm1Dvd/Mif^tm1Dvd	B6.129S4-Mif^tm1Dvd