Phenotype Image Detail

Image

Caption

Gross morphology of yolk sac (C,D) and embryo proper (E, F) of wild type (left) and Acvrl1^tm1Enl/Acvrl1^tm1Enl embryos (right) at E9.5 (C,E) and E10.5 (D,F). Arrows with asterisks (C) indicate yolk sac blood vessels. Arrows (F) indicate clumps of blood cells in the mutant embryos. pc, pericardium. (G, H) Histological analysis of E9.5 wild type (G) and mutant (H) embryos in decidua. In the mutant yolk sac, blood, and endothelial cells (EC) are present, but vessels are enlarged (H). bc, blood cells; d, decidua; en, endothelium.

Copyright

This image is from Oh SP, Proc Natl Acad Sci U S A 2000 Mar 14;97(6):2626-31. Copyright 2000 National Academy of Sciences, U.S.A. J:61177

Associated Alleles

Symbol	Name
Acvrl1^tm1Enl	activin A receptor, type II-like 1; targeted mutation 1, En Li

Associated Genotypes

Allelic Composition	Genetic Background
Acvrl1^tm1Enl/Acvrl1^tm1Enl	involves: C57BL/6