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Phenotype Image Detail
Image
Caption Gross photomicrograph of atrophy in 9 month old Cptm1Hrs/Cptm1Hrs Hephsla/Y (Cp-/-Heph-/Y) retina. After removal of the cornea and lens, wild-type eye cup (A) has a transillumination only at the optic nerve. In contrast, the Cptm1Hrs/Cptm1Hrs Hephsla/Y (B) has areas of depigmentation (arrows) consistent with retinal pigment epithelium (RPE) pigment loss and atrophy in the peripheral retina.
Copyright This image is from Hahn P, Proc Natl Acad Sci U S A 2004 Sep 21;101(38):13850-5. Copyright 2004 National Academy of Sciences, U.S.A. J:92620
Associated
Alleles
Symbol Name
Cptm1Hrs ceruloplasmin; targeted mutation 1, Z Leah Harris
Hephsla hephaestin; sex-linked anemia
Associated
Genotypes
Allelic Composition Genetic Background
Cptm1Hrs/Cptm1Hrs
Hephsla/Y
involves: 129X1/SvJ * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory