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Phenotype Image Detail
Image
Caption In contrast to the wild type mammary glands (A,B), the Gja1tm7(Gja2)Kwi/Gja1+ mammary glands (C,D) show a dramatically reduced branching of the ductuli. As a consequence, less alveoli surrounded by adipocytic tissue were seen (compare A with C). The alveoli were mostly smaller in diameter but did show apocrine secretion and milk droplets in the lumen (arrow, D).
Copyright This image is from Winterhager E, BMC Dev Biol 2007;7():26, an open-access article, licensee BioMed Central Ltd. J:126511
Associated
Alleles
Symbol Name
Gja1tm7(Gja2)Kwi gap junction protein, alpha 1; targeted mutation 7, Klaus Willecke
Associated
Genotypes
Allelic Composition Genetic Background
Gja1tm7(Gja2)Kwi/Gja1+ involves: 129P2/OlaHsd * C57BL/6 * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory