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Phenotype Image Detail
Image
Caption Brightfield view of the aortic arches collected from 26 week old control (A) and Plgtm1Jld/Plgtm1Jld mice (B). Comparable views of typical arches collected from 22 week old ( C & D) and 25 week old (E & F), Apoetm1Bres/Apoetm1Bres (C & E) and Apoetm1Bres/Apoetm1Bres Plgtm1Jld/Plgtm1Jld (D & F) mice. Note the dark appearing atherosclerotic lesions along the lesser curvature (asterisk), brachiocephalic trunk (single arrow), left common carotid (double arrowheads), and left subclavian (double arrows). Under darkfield, the lesions appear as opaque, cream colored deposits. Scale bar 1mm
Copyright This image is from Xiao Q, Proc Natl Acad Sci U S A 1997 Sep 16;94(19):10335-40. Copyright 1997 National Academy of Sciences, U.S.A. J:42927
Associated
Alleles
Symbol Name
Apoetm1Bres apolipoprotein E; targeted mutation 1, Jan L Breslow
Plgtm1Jld plasminogen; targeted mutation 1, Jay L Degen
Associated
Genotypes
Allelic Composition Genetic Background
Plgtm1Jld/Plgtm1Jld involves: 129P2/OlaHsd * C57BL/6 * NIH Black Swiss
Apoetm1Bres/Apoetm1Bres
Plgtm1Jld/Plgtm1Jld
involves: 129P2/OlaHsd * C57BL/6 * NIH Black Swiss
Apoetm1Bres/Apoetm1Bres involves: 129P2/OlaHsd * C57BL/6 * NIH Black Swiss

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory