Phenotype Image Detail

Image

Caption

A: Transverse and longitudinal profiles of the connecting cilia (CC). Rpgrip1^tm1Tili/Rpgrip1^tm1Tili and wild type mouse CC appear similar in the microtubule arrays, transmembrane assemblings, and ciliary necklaces. B: Longitudinal sections through wild type mouse photoreceptor, illustrating the normal morphology of the apical inner segment, CC and outer segment. C: In the homozygous mutant, disk diameters are greatly expanded and orientation is altered. Enlarged disks appear bending upward (left) or downward (right). D: A lower-magnification image of the mutant mouse retina showing several photoreceptors. Abbreviations: OS: outer segment; IS: inner segment. Scale bars: 0.2um

Copyright

This image is from Zhao Y, Proc Natl Acad Sci U S A 2003 Apr 1;100(7):3965-70. Copyright 2003 National Academy of Sciences, U.S.A. J:82755

Associated Alleles

Symbol	Name
Rpgrip1^tm1Tili	retinitis pigmentosa GTPase regulator interacting protein 1; targeted mutation 1, Tiansen Li

Associated Genotypes

Allelic Composition	Genetic Background
Rpgrip1^tm1Tili/Rpgrip1^tm1Tili	involves: 129S4/SvJae * C57BL/6