About   Help   FAQ
Phenotype Image Detail
Image
Caption A-E: Radiographs of front paws (A & B) and hindpaws (C-E) of 7 month old wild type (A & C), FgrMhdaali18/Ali18+ (D) and FgrMhdaali18/FgrMhdaali18 mice. Phalanges of the homozygote are affected. Open boxes indicate destruction of bones and joints. F-I: Reconstructed images from microcomputed tomography scans. Khaki-colored regions indicate calcified bone tissue in black background, and pink areas mark sectioned surfaces. Sagittal sections of lumbar vertebrae are shown in (F) wild type and (G) homozygous mutant mice. Blue lines in (G) indicate reduced bone density in vertebral bodies and arches in the homozygous mutant mouse. Sagittal sections of the knee joint region shown in (H) wild type and (I) homozygous mutant mice. Increased bone marrow regions of mutant femur are indicated by asterisks.
Copyright This image is from Abe K, Mamm Genome 2006 Sep;17(9):915-26 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:112868
Associated
Alleles
Symbol Name
FgrMhdaali18 FGR proto-oncogene, Src family tyrosine kinase; Abnormal limb
Associated
Genotypes
Allelic Composition Genetic Background
FgrMhdaali18/FgrMhdaali18 C3HeB/FeJ-FgrMhdaali18

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/18/2022
MGI 6.17
The Jackson Laboratory