Phenotype Image Detail

Image

Caption

A: Reduced testes size in Kiss1^tm1Coll/Kiss1^tm1Coll mice. B: Reduced development of seminal vesicle in mutant mice. C & D: Histology of seminiferous tubules showing intact spermatogenesis and mature sperm in wild type mice (C) and impaired spermatogenesis in mutant mice (D). E & F: Histology of epididymis showing sperm in the lumen (I) in wild type mice (E) and absence of sperm in the lumen in mutant mice (F). G & H: Histology of adrenal gland showing retention of fetal zone X (arrow) in mutant male mice (H) and absence of this zone in mature male wild type mice (G). Scale bars: A & B: 0.25cm; C-F: 50um; G & H: 300um

Copyright

This image is from d'Anglemont de Tassigny X, Proc Natl Acad Sci U S A 2007 Jun 19;104(25):10714-9. Copyright 2007 National Academy of Sciences, U.S.A. J:122381

Associated Alleles

Symbol	Name
Kiss1^tm1Coll	KiSS-1 metastasis-suppressor; targeted mutation 1, William H Colledge

Associated Genotypes

Allelic Composition	Genetic Background
Kiss1^tm1Coll/Kiss1^tm1Coll	involves: 129S/SvEv * 129S6/SvEvTac