Phenotype Image Detail

Image

Caption

B: Tails from adult wild type (right) and Blmh^tm1Geh/Blmh^tm1Geh mice. C-F: Hematoxylin and eosin stained cross sections (6um) of tail biopsies from wild type (C) and homozygous mutant mice(D-F). The arrowheads in D and E identify ballooning degeneration of the stratum spinosum. F: Full thickness necrosis and abundant neutrophil infiltrate (arrow), from a homozygous mutant mouse with severe dermatitis. Abbreviations: Ballooning degeneration (BD); stratum basale (SB); stratum corneum (SC); stratum granulosum (SG); stratum spinosum (SS); parakeratosis (PK) Scalebars: 25um

Copyright

This image is from Schwartz DR, Proc Natl Acad Sci U S A 1999 Apr 13;96(8):4680-5. Copyright 1999 National Academy of Sciences, U.S.A. J:54585

Associated Alleles

Symbol	Name
Blmh^tm1Geh	bleomycin hydrolase; targeted mutation 1, Gregg E Homanics

Associated Genotypes

Allelic Composition	Genetic Background
Blmh^tm1Geh/Blmh^tm1Geh	either: (involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)