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Phenotype Image Detail
Image
Caption A & B: Oil-Red-O staining of frozen liver sections of 4-5 week old Acadltm1Uab/Acadl+ (left) and Acadltm1Uab/Acadltm1Uab (right) mice after 18 to 20 hour fast indicate large lipid droplets present in the Acadltm1Uab/Acadltm1Uab mouse. C & D: Comparison of frozen hearts from 14-16 week old Acadltm1Uab/Acadl+ (left) and Acadltm1Uab/Acadltm1Uab (right) mice after 18 to 20 hour fast shows an accumulation in all cardiomyocytes in the Acadltm1Uab/Acadltm1Uab mouse. E & F: Hemotoxylin-eosin stained heart sections of 16 week old Acadltm1Uab/Acadl+ (left) and Acadltm1Uab/Acadltm1Uab (right) nonfasted mice reveals there is prominent myocardial degeneration and fibrosis (arrows) in the Acadltm1Uab/Acadltm1Uab mouse. Magnification: A & B: X25; C & D: X40; E & F: X10
Copyright This image is from Kurtz DM, Proc Natl Acad Sci U S A 1998 Dec 22;95(26):15592-7. Copyright 1998 National Academy of Sciences, U.S.A. J:51660
Associated
Alleles
Symbol Name
Acadltm1Uab acyl-Coenzyme A dehydrogenase, long-chain; targeted mutation 1, University of Alabama
Associated
Genotypes
Allelic Composition Genetic Background
Acadltm1Uab/Acadltm1Uab involves: 129S6/SvEvTac * C57BL/6NTac

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory