TYR Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	TYR	HGNC:12442 (HGNC) 7299 (Entrez Gene) 606933 (OMIM) TYR (Alliance of Genome Resources)	Chr11 q14.3	Chr11:89177875-89295759 (+) GRCh38	melanoma ocular albinism 1 oculocutaneous albinism oculocutaneous albinism type IA oculocutaneous albinism type IB pigmentation disease retinoschisis skin melanoma vitiligo	P14679 (UniProt \| EBI) NM_000372 (RefSeq)
mouse	Tyr	MGI:98880 (MGI) 22173 (Entrez Gene) Gene Tree Tyr (Alliance of Genome Resources)	Chr7 49.01 cM	Chr7:87073979-87142637 (-) GRCm39	buphthalmos oculocutaneous albinism	22173 (NCBI Gene Model) P11344 (UniProt \| EBI) NM_011661 (RefSeq)
rat	Tyr	RGD:1589755 (Rat Genome Database) 308800 (Entrez Gene) Tyr (Alliance of Genome Resources)	Chr1 q32			NP_001101005 (RefSeq) NM_001107535 (RefSeq)
zebrafish	tyr	ZDB-GENE-991026-3 (Zebrafish Model Organism Database) 30207 (Entrez Gene) tyr (Alliance of Genome Resources)	Chr15			NP_571088 (RefSeq) NM_131013 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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