SCN1A Vertebrate HGNC

About Help FAQ

Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	SCN1A	HGNC:10585 (HGNC) 6323 (Entrez Gene) 182389 (OMIM) SCN1A (Alliance of Genome Resources)	Chr2 q24.3	Chr2:165984641-166149214 (-) GRCh38	developmental and epileptic encephalopathy 6B Dravet syndrome familial hemiplegic migraine 3 generalized epilepsy with febrile seizures plus generalized epilepsy with febrile seizures plus 2	P35498 (UniProt \| EBI) NM_001353957 (RefSeq)
mouse	Scn1a	MGI:98246 (MGI) 20265 (Entrez Gene) Gene Tree Scn1a (Alliance of Genome Resources)	Chr2 39.13 cM	Chr2:66101125-66271181 (-) GRCm39	autism spectrum disorder Dravet syndrome generalized epilepsy with febrile seizures plus	20265 (NCBI Gene Model) A2APX8 (UniProt \| EBI) NM_001313997 (RefSeq)
rat	Scn1a	RGD:69364 (Rat Genome Database) 81574 (Entrez Gene) Scn1a (Alliance of Genome Resources)	Chr3 q21			P04774 (UniProt \| EBI) NM_030875 (RefSeq)
zebrafish	scn1laa	ZDB-GENE-040426-751 (Zebrafish Model Organism Database) 393101 (Entrez Gene) scn1laa (Alliance of Genome Resources)	Chr9			NP_956426 (RefSeq) NM_200132 (RefSeq)
zebrafish	scn1lab	ZDB-GENE-060906-1 (Zebrafish Model Organism Database) 559447 (Entrez Gene) scn1lab (Alliance of Genome Resources)	Chr6			NP_001038360 (RefSeq) NM_001044895 (RefSeq)