PRF1 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	PRF1	HGNC:9360 (HGNC) 5551 (Entrez Gene) 170280 (OMIM) PRF1 (Alliance of Genome Resources)	Chr10 q22.1	Chr10:70597348-70602759 (-) GRCh38	aplastic anemia Crohn's disease familial hemophagocytic lymphohistiocytosis 2 human immunodeficiency virus infectious disease multiple sclerosis non-Hodgkin lymphoma non-Langerhans-cell histiocytosis	P14222 (UniProt \| EBI) NM_005041 (RefSeq)
mouse	Prf1	MGI:97551 (MGI) 18646 (Entrez Gene) Gene Tree Prf1 (Alliance of Genome Resources)	Chr10 32.18 cM	Chr10:61133612-61140459 (+) GRCm39	familial hemophagocytic lymphohistiocytosis 2 multiple sclerosis type 1 diabetes mellitus	ENSMUSG00000037202 (Ensembl Gene Model) ENSMUSP00000151354 (Ensembl) ENSMUST00000219375 (Ensembl)
rat	Prf1	RGD:708463 (Rat Genome Database) 50669 (Entrez Gene) Prf1 (Alliance of Genome Resources)	Chr20 q11			P35763 (UniProt \| EBI) NM_017330 (RefSeq)
zebrafish	prf1.1	ZDB-GENE-111212-2 (Zebrafish Model Organism Database) 100000903 (Entrez Gene) prf1.1 (Alliance of Genome Resources)	Chr3			NP_001304691 (RefSeq) NM_001317762 (RefSeq)
	prf1.2	ZDB-GENE-111212-3 (Zebrafish Model Organism Database) 103909237 (Entrez Gene) prf1.2 (Alliance of Genome Resources)	Chr19			NP_001304689 (RefSeq) NM_001317760 (RefSeq)
	prf1.3	ZDB-GENE-060503-461 (Zebrafish Model Organism Database) 559849 (Entrez Gene) prf1.3 (Alliance of Genome Resources)	Chr19			NP_001304696 (RefSeq) NM_001317767 (RefSeq)
	prf1.5	ZDB-GENE-081105-3 (Zebrafish Model Organism Database) 559384 (Entrez Gene) prf1.5 (Alliance of Genome Resources)	Chr8			NP_001116718 (RefSeq) NM_001123246 (RefSeq)
	prf1.6	ZDB-GENE-070410-126 (Zebrafish Model Organism Database) 795573 (Entrez Gene) prf1.6 (Alliance of Genome Resources)	Chr8			NP_001082976 (RefSeq) NM_001089507 (RefSeq)
	prf1.7	ZDB-GENE-111212-11 (Zebrafish Model Organism Database) 100535230 (Entrez Gene) prf1.7 (Alliance of Genome Resources)	Chr19			XP_003200648 (RefSeq)
	prf1.8	ZDB-GENE-111212-12 (Zebrafish Model Organism Database) 103909247 (Entrez Gene) prf1.8 (Alliance of Genome Resources)	Chr19			XP_009292559 (RefSeq)
	prf1.9	ZDB-GENE-131127-344 (Zebrafish Model Organism Database) 569443 (Entrez Gene) prf1.9 (Alliance of Genome Resources)	Chr3			NP_001304687 (RefSeq) NM_001317758 (RefSeq)