NOTCH1 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	NOTCH1	HGNC:7881 (HGNC) 4851 (Entrez Gene) 190198 (OMIM) NOTCH1 (Alliance of Genome Resources)	Chr9 q34.3	Chr9:136494433-136546048 (-) GRCh38	Adams-Oliver syndrome adult T-cell leukemia/lymphoma aortic valve disease 1 congenital heart disease	P46531 (UniProt \| EBI) NM_017617 (RefSeq)
mouse	Notch1	MGI:97363 (MGI) 18128 (Entrez Gene) Gene Tree Notch1 (Alliance of Genome Resources)	Chr2 18.91 cM	Chr2:26347914-26393834 (-) GRCm39		18128 (NCBI Gene Model) Q01705 (UniProt \| EBI) NM_008714 (RefSeq)
rat	Notch1	RGD:3187 (Rat Genome Database) 25496 (Entrez Gene) Notch1 (Alliance of Genome Resources)	Chr3 p13			Q07008 (UniProt \| EBI) NM_001105721 (RefSeq)
zebrafish	notch1a	ZDB-GENE-990415-173 (Zebrafish Model Organism Database) 30718 (Entrez Gene) notch1a (Alliance of Genome Resources)	Chr21			P46530 (UniProt \| EBI) NM_131441 (RefSeq)
zebrafish	notch1b	ZDB-GENE-990415-183 (Zebrafish Model Organism Database) 794892 (Entrez Gene) notch1b (Alliance of Genome Resources)	Chr5			NP_571377 (RefSeq) NM_131302 (RefSeq)