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Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IDH2 HGNC:5383 (HGNC)
3418 (Entrez Gene)
147650 (OMIM)
IDH2 (Alliance of Genome Resources)
Chr15 q26.1 Chr15:90083045-90102477 (-)
GRCh38
acute myeloid leukemia
D-2-hydroxyglutaric aciduria 2
esophagus squamous cell carcinoma
hepatocellular clear cell carcinoma
intrahepatic cholangiocarcinoma
lung cancer
lung non-small cell carcinoma
lung squamous cell carcinoma
P48735 (UniProt | EBI)
NM_001289910 (RefSeq)
mouse Idh2 MGI:96414 (MGI)
269951 (Entrez Gene)
Gene Tree
Idh2 (Alliance of Genome Resources)
Chr7 45.43 cM Chr7:79744594-79765140 (-)
GRCm39
bone remodeling disease
ENSMUSG00000030541 (Ensembl Gene Model)
ENSMUSP00000103007 (Ensembl)
ENSMUST00000107384 (Ensembl)
rat Idh2 RGD:1597139 (Rat Genome Database)
361596 (Entrez Gene)
Idh2 (Alliance of Genome Resources)
Chr1 q31 P56574 (UniProt | EBI)
NM_001014161 (RefSeq)
zebrafish idh2 ZDB-GENE-031118-95 (Zebrafish Model Organism Database)
386951 (Entrez Gene)
idh2 (Alliance of Genome Resources)
Chr18 NP_955858 (RefSeq)
NM_199564 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory