DDC Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	DDC	HGNC:2719 (HGNC) 1644 (Entrez Gene) 107930 (OMIM) DDC (Alliance of Genome Resources)	Chr7 p12.2-p12.1	Chr7:50458436-50565405 (-) GRCh38	aromatic L-amino acid decarboxylase deficiency bipolar disorder inherited metabolic disorder Parkinson's disease	P20711 (UniProt \| EBI) NM_001242887 (RefSeq)
mouse	Ddc	MGI:94876 (MGI) 13195 (Entrez Gene) Gene Tree Ddc (Alliance of Genome Resources)	Chr11 7.09 cM	Chr11:11764101-11848144 (-) GRCm39	aromatic L-amino acid decarboxylase deficiency	13195 (NCBI Gene Model) O88533 (UniProt \| EBI) NM_001417459 (RefSeq)
rat	Ddc	RGD:2494 (Rat Genome Database) 24311 (Entrez Gene) Ddc (Alliance of Genome Resources)	Chr14 q21			P14173 (UniProt \| EBI) NM_012545 (RefSeq)
zebrafish	ddc	ZDB-GENE-040426-2656 (Zebrafish Model Organism Database) 406651 (Entrez Gene) ddc (Alliance of Genome Resources)	Chr16			NP_998507 (RefSeq) NM_213342 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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