NOD2 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	NOD2	HGNC:5331 (HGNC) 64127 (Entrez Gene) 605956 (OMIM) NOD2 (Alliance of Genome Resources)	Chr16 q12.1	Chr16:50693588-50733077 (+) GRCh38	asthma autoimmune disease Behcet's disease Blau syndrome breast cancer bronchiolitis obliterans chronic obstructive pulmonary disease colorectal adenocarcinoma coronary artery disease Crohn's disease familial mediterranean fever gastritis gastrointestinal carcinoma graft-versus-host disease intestinal disease larynx cancer leprosy lung cancer meningococcal meningitis ovarian cancer pulmonary sarcoidosis pulmonary tuberculosis relapsing-remitting multiple sclerosis rhinitis systemic lupus erythematosus	Q9HC29 (UniProt \| EBI) NM_001370466 (RefSeq)
mouse	Nod2	MGI:2429397 (MGI) 257632 (Entrez Gene) Gene Tree Nod2 (Alliance of Genome Resources)	Chr8 43.51 cM	Chr8:89373943-89415102 (+) GRCm39	inflammatory bowel disease 1	ENSMUSG00000055994 (Ensembl Gene Model) ENSMUSP00000050538 (Ensembl) ENSMUST00000054324 (Ensembl)
rat	Nod2	RGD:1306368 (Rat Genome Database) 291912 (Entrez Gene) Nod2 (Alliance of Genome Resources)	Chr19 p11			NP_001401840 (RefSeq) NM_001106172 (RefSeq)
zebrafish	nod2	ZDB-GENE-061108-4 (Zebrafish Model Organism Database) 777696 (Entrez Gene) nod2 (Alliance of Genome Resources)	Chr7			NP_001314973 (RefSeq) NM_001328044 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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