IRF6 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	IRF6	HGNC:6121 (HGNC) 3664 (Entrez Gene) 607199 (OMIM) IRF6 (Alliance of Genome Resources)	Chr1 q32.2	Chr1:209785617-209806175 (-) GRCh38	cleft lip cleft palate orofacial cleft 6 popliteal pterygium syndrome syndactyly Van der Woude syndrome	O14896 (UniProt \| EBI) NM_001206696 (RefSeq)
mouse	Irf6	MGI:1859211 (MGI) 54139 (Entrez Gene) Gene Tree Irf6 (Alliance of Genome Resources)	Chr1 97.6 cM	Chr1:192835419-192854331 (+) GRCm39	cleft lip popliteal pterygium syndrome Van der Woude syndrome	ENSMUSG00000026638 (Ensembl Gene Model) ENSMUSP00000075839 (Ensembl) ENSMUST00000076521 (Ensembl)
rat	Irf6	RGD:1309645 (Rat Genome Database) 364081 (Entrez Gene) Irf6 (Alliance of Genome Resources)	Chr13 q27			NP_001102329 (RefSeq) NM_001108859 (RefSeq)
zebrafish	irf6	ZDB-GENE-040426-1137 (Zebrafish Model Organism Database) 393570 (Entrez Gene) irf6 (Alliance of Genome Resources)	Chr22			NP_956892 (RefSeq) NM_200598 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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