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Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FTO HGNC:24678 (HGNC)
79068 (Entrez Gene)
610966 (OMIM)
FTO (Alliance of Genome Resources)
Chr16 q12.2 Chr16:53701692-54158512 (+)
GRCh38
aortic valve disease 2
cardiovascular system disease
clear cell renal cell carcinoma
coronary artery disease
diabetic neuropathy
essential hypertension
hypertension
myocardial infarction
nuclear senile cataract
obesity
pulmonary embolism
renal cell carcinoma
type 2 diabetes mellitus
Q9C0B1 (UniProt | EBI)
NM_001363896 (RefSeq)
mouse Fto MGI:1347093 (MGI)
26383 (Entrez Gene)
Gene Tree
Fto (Alliance of Genome Resources)
Chr8 44.34 cM Chr8:92040153-92395067 (+)
GRCm39
ENSMUSG00000055932 (Ensembl Gene Model)
ENSMUSP00000068380 (Ensembl)
ENSMUST00000069718 (Ensembl)
rat Fto RGD:1305121 (Rat Genome Database)
291905 (Entrez Gene)
Fto (Alliance of Genome Resources)
Chr19 p11 Q2A121 (UniProt | EBI)
NM_001039713 (RefSeq)
zebrafish fto ZDB-GENE-061108-1 (Zebrafish Model Organism Database)
553363 (Entrez Gene)
fto (Alliance of Genome Resources)
Chr7 XP_009301626 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory