MAPK1 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	MAPK1	HGNC:6871 (HGNC) 5594 (Entrez Gene) 176948 (OMIM) MAPK1 (Alliance of Genome Resources)	Chr22 q11.22	Chr22:21759657-21867680 (-) GRCh38	colon adenocarcinoma colorectal adenocarcinoma endometrial adenocarcinoma Noonan syndrome 13 prostate adenocarcinoma pulmonary hypertension renal cell carcinoma	P28482 (UniProt \| EBI) NM_002745 (RefSeq)
mouse	Mapk1	MGI:1346858 (MGI) 26413 (Entrez Gene) Gene Tree Mapk1 (Alliance of Genome Resources)	Chr16 10.53 cM	Chr16:16801246-16865317 (+) GRCm39	autism spectrum disorder velocardiofacial syndrome Weissenbacher-Zweymuller syndrome	26413 (NCBI Gene Model) P63085 (UniProt \| EBI) NM_011949 (RefSeq)
rat	Mapk1	RGD:70500 (Rat Genome Database) 116590 (Entrez Gene) Mapk1 (Alliance of Genome Resources)	Chr11 q23			P63086 (UniProt \| EBI) NM_053842 (RefSeq)
zebrafish	mapk1	ZDB-GENE-030722-2 (Zebrafish Model Organism Database) 360144 (Entrez Gene) mapk1 (Alliance of Genome Resources)	Chr5			NP_878308 (RefSeq) NM_182888 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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