MRE11 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	MRE11	HGNC:7230 (HGNC) 4361 (Entrez Gene) 600814 (OMIM) MRE11 (Alliance of Genome Resources)	Chr11 q21	Chr11:94415570-94512412 (-) GRCh38	ataxia-telangiectasia-like disorder-1 breast carcinoma colon cancer endometrial cancer Lynch syndrome rectum cancer stomach carcinoma urinary bladder cancer	P49959 (UniProt \| EBI) NM_005591 (RefSeq)
mouse	Mre11a	MGI:1100512 (MGI) 17535 (Entrez Gene) Gene Tree Mre11a (Alliance of Genome Resources)	Chr9 4.33 cM	Chr9:14695971-14748421 (+) GRCm39		17535 (NCBI Gene Model) Q61216 (UniProt \| EBI) NM_001411899 (RefSeq)
rat	Mre11	RGD:69263 (Rat Genome Database) 64046 (Entrez Gene) Mre11 (Alliance of Genome Resources)	Chr8 q12			Q9JIM0 (UniProt \| EBI) NM_022279 (RefSeq)
zebrafish	mre11a	ZDB-GENE-040426-2638 (Zebrafish Model Organism Database) 406637 (Entrez Gene) mre11a (Alliance of Genome Resources)	Chr15			NP_001307188 (RefSeq) NM_001001407 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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