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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CACNA1A HGNC:1388 (HGNC)
773 (Entrez Gene)
601011 (OMIM)
Chr19 p13 Chr19:13206442-13506460 (-)
Episodic Ataxia, Type 2; EA2
Migraine, Familial Hemiplegic, 1; FHM1
Spinocerebellar Ataxia 6; SCA6
O00555 (UniProt | EBI)
NM_001127221 (RefSeq)
mouse Cacna1a MGI:109482 (MGI)
12286 (Entrez Gene)
Gene Tree
Chr8 40.95 cM Chr8:84388440-84640246 (+)
Migraine, Familial Hemiplegic, 1; FHM1
Spinocerebellar Ataxia 6; SCA6
OTTMUSG00000031448 (VEGA)
OTTMUSP00000041322 (VEGA)
OTTMUST00000077929 (VEGA)
rat Cacna1a 25398 (Entrez Gene)
Chr19 q11 P54282 (UniProt | EBI)
NM_012918 (RefSeq)
chimpanzee CACNA1A 455766 (Entrez Gene)
Chr19 XP_009433169 (RefSeq)
rhesus macaque CACNA1A 718291 (Entrez Gene)
Chr19 XP_002801141 (RefSeq)
cattle CACNA1A 282648 (Entrez Gene)
Chr7 NP_001068597 (RefSeq)
NM_001075129 (RefSeq)
dog CACNA1A 100686650 (Entrez Gene)
Chr20 XP_005632867 (RefSeq)
western clawed frog cacna1a 100492135 (Entrez Gene)
ChrUN XP_002940668 (RefSeq)
zebrafish cacna1ab 569528 (Entrez Gene)
Chr11 XP_009304409 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory