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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CACNA1A HGNC:1388 (HGNC)
773 (Entrez Gene)
601011 (OMIM)
Cav2.1 (MyGene.info)
HGNC homology
Chr19 p13.13 Chr19:13206442-13506460 (-)
episodic ataxia type 2
familial hemiplegic migraine
spinocerebellar ataxia type 6
O00555 (UniProt | EBI)
NM_001174080 (RefSeq)
mouse Cacna1a MGI:109482 (MGI)
12286 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 40.95 cM Chr8:84388440-84640246 (+)
cerebellar ataxia
childhood electroclinical syndrome
episodic ataxia type 2
familial hemiplegic migraine
generalized dystonia
Lambert-Eaton myasthenic syndrome
spinocerebellar ataxia type 6
OTTMUSG00000031448 (VEGA)
OTTMUSP00000041322 (VEGA)
OTTMUST00000077929 (VEGA)
rat Cacna1a 25398 (Entrez Gene)
Chr19 q11 P54282 (UniProt | EBI)
NM_012918 (RefSeq)
chimpanzee CACNA1A 455766 (Entrez Gene)
Chr19 XP_016790746 (RefSeq)
cattle CACNA1A 282648 (Entrez Gene)
Chr7 NP_001068597 (RefSeq)
NM_001075129 (RefSeq)
dog CACNA1A 100686650 (Entrez Gene)
Chr20 XP_013977279 (RefSeq)
zebrafish cacna1ab 569528 (Entrez Gene)
Chr11 NP_001315637 (RefSeq)
NM_001328708 (RefSeq)
frog, western clawed cacna1a 100492135 (Entrez Gene)
Chr3 XP_017948182 (RefSeq)
macaque, rhesus CACNA1A 718291 (Entrez Gene)
Chr19 XP_014978562 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory