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Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ABCA4 HGNC:34 (HGNC)
24 (Entrez Gene)
601691 (OMIM)
ABCA4 (Alliance of Genome Resources)
Chr1 p22.1 Chr1:93992834-94121148 (-)
GRCh38
age related macular degeneration 2
cone-rod dystrophy 3
fundus dystrophy
macular degeneration
retinal degeneration
retinitis pigmentosa
retinitis pigmentosa 19
P78363 (UniProt | EBI)
NM_000350 (RefSeq)
mouse Abca4 MGI:109424 (MGI)
11304 (Entrez Gene)
Gene Tree
Abca4 (Alliance of Genome Resources)
Chr3 52.94 cM Chr3:121838092-121973772 (+)
GRCm39
cone-rod dystrophy 3
retinitis pigmentosa 19
Stargardt disease
ENSMUSG00000028125 (Ensembl Gene Model)
ENSMUSP00000013995 (Ensembl)
ENSMUST00000013995 (Ensembl)
rat Abca4 RGD:1309445 (Rat Genome Database)
310836 (Entrez Gene)
Abca4 (Alliance of Genome Resources)
Chr2 q42 NP_001101191 (RefSeq)
NM_001107721 (RefSeq)
zebrafish abca4a ZDB-GENE-050517-3 (Zebrafish Model Organism Database)
798993 (Entrez Gene)
abca4a (Alliance of Genome Resources)
Chr24 NP_001002206 (RefSeq)
NM_001002206 (RefSeq)
abca4b ZDB-GENE-050517-4 (Zebrafish Model Organism Database)
555506 (Entrez Gene)
abca4b (Alliance of Genome Resources)
Chr2 XP_005163385 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory