IL18 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	IL18	HGNC:5986 (HGNC) 3606 (Entrez Gene) 600953 (OMIM) IL18 (Alliance of Genome Resources)	Chr11 q23.1	Chr11:112143253-112164096 (-) GRCh38	allergic rhinitis alopecia areata asthma atopic dermatitis Behcet's disease biliary atresia breast cancer eye disease hepatitis B hepatitis C hepatocellular carcinoma Kawasaki disease lung disease respiratory syncytial virus infectious disease sleep apnea temporal arteritis urticaria	Q14116 (UniProt \| EBI) NM_001386420 (RefSeq)
mouse	Il18	MGI:107936 (MGI) 16173 (Entrez Gene) Gene Tree Il18 (Alliance of Genome Resources)	Chr9 27.75 cM	Chr9:50466127-50493140 (+) GRCm39	atopic dermatitis	ENSMUSG00000039217 (Ensembl Gene Model) ENSMUSP00000151002 (Ensembl) ENSMUST00000214117 (Ensembl)
rat	Il18	RGD:2889 (Rat Genome Database) 29197 (Entrez Gene) Il18 (Alliance of Genome Resources)	Chr8 q23			P97636 (UniProt \| EBI) NM_019165 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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