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Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HLA-DQB1 HGNC:4944 (HGNC)
3119 (Entrez Gene)
604305 (OMIM)
HLA-DQB1 (Alliance of Genome Resources)
Chr6 p21.32 Chr6:32659467-32668383 (-)
GRCh38
achalasia
acute disseminated encephalomyelitis
acute lymphoblastic leukemia
acute myeloid leukemia
Addison's disease
agranulocytosis
allergic bronchopulmonary aspergillosis
allergic disease
alopecia areata
alveolar echinococcosis
ankylosing spondylitis
antiphospholipid syndrome
aplastic anemia
arthritis
aspirin-induced respiratory disease
asthma
atrophic gastritis
autoimmune disease
autoimmune hepatitis
autoimmune pancreatitis
autoimmune polyendocrine syndrome
autoimmune polyendocrine syndrome type 2
autoimmune thrombocytopenic purpura
autoimmune thyroiditis
bacterial infectious disease
Behcet's disease
beta thalassemia
celiac disease
cervical cancer
cervical dystonia
chikungunya
choreatic disease
chronic myeloid leukemia
cicatricial pemphigoid
colorectal cancer
common variable immunodeficiency
common wart
Creutzfeldt-Jakob disease
Crohn's disease
cystic echinococcosis
degenerative myopia
dental caries
diabetic retinopathy
dilated cardiomyopathy
dilated cardiomyopathy 1H
erythema multiforme
glaucoma
Graves' disease
hepatitis B
hepatitis C
hepatocellular carcinoma
human immunodeficiency virus infectious disease
hyperthyroidism
hypothyroidism
IgA glomerulonephritis
immunoglobulin alpha deficiency
iridocyclitis
juvenile rheumatoid arthritis
latex allergy
liver cirrhosis
marginal zone lymphoma
multidrug-resistant tuberculosis
multiple sclerosis
myasthenia gravis
mycosis fungoides
myocarditis
myositis
narcolepsy
neuromyelitis optica
optic neuritis
osteomyelitis
paroxysmal nocturnal hemoglobinuria
pemphigus
pemphigus vulgaris
Plasmodium falciparum malaria
pneumoconiosis
pre-eclampsia
primary progressive multiple sclerosis
primary sclerosing cholangitis
psoriasis
pulmonary tuberculosis
pure red-cell aplasia
rheumatic fever
rheumatic heart disease
rheumatoid arthritis
rhinitis
rhinoscleroma
sarcoidosis
sickle cell anemia
silicosis
Sjogren's syndrome
Stevens-Johnson syndrome
stomach disease
systemic lupus erythematosus
thrombotic thrombocytopenic purpura
tropical spastic paraparesis
tuberculosis
type 1 diabetes mellitus
typhoid fever
ulcerative colitis
vitiligo
Vogt-Koyanagi-Harada disease
vulva cancer
P01920 (UniProt | EBI)
NM_002123 (RefSeq)
HLA-DQB2 HGNC:4945 (HGNC)
3120 (Entrez Gene)
615161 (OMIM)
HLA-DQB2 (Alliance of Genome Resources)
Chr6 p21.32 Chr6:32756098-32763532 (-)
GRCh38
P05538 (UniProt | EBI)
NM_182549 (RefSeq)
mouse H2-Ab1 MGI:103070 (MGI)
14961 (Entrez Gene)
Gene Tree
H2-Ab1 (Alliance of Genome Resources)
Chr17 17.98 cM Chr17:34482201-34488392 (+)
GRCm39
14961 (NCBI Gene Model)
P06342 (UniProt | EBI)
NM_207105 (RefSeq)
rat RT1-B RGD:3467 (Rat Genome Database)
24738 (Entrez Gene)
RT1-B (Alliance of Genome Resources)
Chr20 P06341 (UniProt | EBI)
RT1-Bb RGD:3469 (Rat Genome Database)
309622 (Entrez Gene)
RT1-Bb (Alliance of Genome Resources)
Chr20 p12 P29826 (UniProt | EBI)
NM_001004084 (RefSeq)
zebrafish mhc2bl ZDB-GENE-030616-99 (Zebrafish Model Organism Database)
368703 (Entrez Gene)
mhc2bl (Alliance of Genome Resources)
Chr8 XP_005167291 (RefSeq)
mhc2d4b ZDB-GENE-030131-4747 (Zebrafish Model Organism Database)
326022 (Entrez Gene)
mhc2d4b (Alliance of Genome Resources)
Chr4 XP_005168179 (RefSeq)
mhc2d8.35b2 ZDB-GENE-030616-171 (Zebrafish Model Organism Database)
563286 (Entrez Gene)
mhc2d8.35b2 (Alliance of Genome Resources)
Chr8 NP_001074102 (RefSeq)
NM_001080633 (RefSeq)
mhc2d8.37b2 ZDB-GENE-091204-413 (Zebrafish Model Organism Database)
100332219 (Entrez Gene)
mhc2d8.37b2 (Alliance of Genome Resources)
Chr8 XP_009302413 (RefSeq)
mhc2d8.45b1 ZDB-GENE-030616-396 (Zebrafish Model Organism Database)
368846 (Entrez Gene)
mhc2d8.45b1 (Alliance of Genome Resources)
Chr8 NP_001001595 (RefSeq)
NM_001001595 (RefSeq)
mhc2dab ZDB-GENE-980526-200 (Zebrafish Model Organism Database)
30762 (Entrez Gene)
mhc2dab (Alliance of Genome Resources)
Chr8 NP_571551 (RefSeq)
NM_131476 (RefSeq)
mhc2dbb ZDB-GENE-010112-2 (Zebrafish Model Organism Database)
767810 (Entrez Gene)
mhc2dbb (Alliance of Genome Resources)
Chr18 NP_001070245 (RefSeq)
NM_001076777 (RefSeq)
mhc2dgb ZDB-GENE-030616-319 (Zebrafish Model Organism Database)
368615 (Entrez Gene)
mhc2dgb (Alliance of Genome Resources)
Chr8 NP_001007207 (RefSeq)
NM_001007206 (RefSeq)
mhc2dhb ZDB-GENE-041010-13 (Zebrafish Model Organism Database)
103911540 (Entrez Gene)
mhc2dhb (Alliance of Genome Resources)
Chr8 NP_001005943 (RefSeq)
NM_001005943 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory