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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
68031

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C3 HGNC:1318 (HGNC)
718 (Entrez Gene)
120700 (OMIM)
Chr19 p13.3-p13.2 Chr19:6677835-6720651 (-)
GRCh38
Complement Component 3 Deficiency, Autosomal Recessive; C3D
Hemolytic Uremic Syndrome, Atypical, Susceptibility to, 5; AHUS5
Macular Degeneration, Age-Related, 9; ARMD9
P01024 (UniProt | EBI)
NM_000064 (RefSeq)
mouse C3 MGI:88227 (MGI)
12266 (Entrez Gene)
Gene Tree
VISTA-Point
Chr17 29.72 cM Chr17:57203970-57228136 (-)
GRCm38
OTTMUSG00000042133 (VEGA)
OTTMUSP00000061702 (VEGA)
OTTMUST00000110561 (VEGA)
rat C3 24232 (Entrez Gene)
Chr9 q11 P01026 (UniProt | EBI)
NM_016994 (RefSeq)
chimpanzee C3 455644 (Entrez Gene)
Chr19 XP_009432757 (RefSeq)
rhesus macaque C3 703613 (Entrez Gene)
Chr19 XP_001091921 (RefSeq)
cattle C3 280677 (Entrez Gene)
Chr7 Q2UVX4 (UniProt | EBI)
NM_001040469 (RefSeq)
dog C3 476728 (Entrez Gene)
Chr20 XP_005633285 (RefSeq)
chicken C3 396370 (Entrez Gene)
Chr1 NP_990736 (RefSeq)
NM_205405 (RefSeq)
western clawed frog c3 100216255 (Entrez Gene)
ChrUN XP_004919146 (RefSeq)
LOC100491968 100491968 (Entrez Gene)
ChrUN XP_002940093 (RefSeq)
LOC100492134 100492134 (Entrez Gene)
ChrUN XP_002940094 (RefSeq)
LOC100492293 100492293 (Entrez Gene)
ChrUN XP_002940095 (RefSeq)
LOC100492966 100492966 (Entrez Gene)
ChrUN XP_002940099 (RefSeq)
LOC100497762 100497762 (Entrez Gene)
ChrUN XP_004919229 (RefSeq)
LOC100497914 100497914 (Entrez Gene)
ChrUN XP_002941061 (RefSeq)
zebrafish c3a.1 321046 (Entrez Gene)
Chr1 NP_571317 (RefSeq)
NM_131242 (RefSeq)
c3a.2 30491 (Entrez Gene)
Chr1 NP_571318 (RefSeq)
NM_131243 (RefSeq)
c3a.3 565074 (Entrez Gene)
Chr1 NP_001032313 (RefSeq)
NM_001037236 (RefSeq)
c3a.6 494039 (Entrez Gene)
Chr1 NP_001008582 (RefSeq)
NM_001008582 (RefSeq)
LOC100331428 100331428 (Entrez Gene)
Chr1 XP_002660623 (RefSeq)
LOC100331492 100331492 (Entrez Gene)
Chr1 XP_009293521 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory