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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ZEB1 HGNC:11642 (HGNC)
6935 (Entrez Gene)
189909 (OMIM)
ZEB1 (MyGene.info)
HGNC homology
Chr10 p11.22 Chr10:31318495-31529814 (+)
Fuchs' endothelial dystrophy
posterior polymorphous corneal dystrophy 3
P37275 (UniProt | EBI)
NM_001323674 (RefSeq)
mouse Zeb1 MGI:1344313 (MGI)
21417 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 4.42 cM Chr18:5591860-5775467 (+)
tropical spastic paraparesis
ENSMUSG00000024238 (Ensembl Gene Model)
ENSMUSP00000025081 (Ensembl)
ENSMUST00000025081 (Ensembl)
rat Zeb1 25705 (Entrez Gene)
Chr17 q12.1 Q62947 (UniProt | EBI)
NM_001308265 (RefSeq)
chimpanzee ZEB1 450387 (Entrez Gene)
Chr10 XP_016818395 (RefSeq)
cattle ZEB1 535183 (Entrez Gene)
Chr13 NP_001193519 (RefSeq)
NM_001206590 (RefSeq)
dog ZEB1 477966 (Entrez Gene)
Chr2 XP_005617094 (RefSeq)
chicken ZEB1 396029 (Entrez Gene)
Chr2 P36197 (UniProt | EBI)
NM_205131 (RefSeq)
zebrafish zeb1b 114425 (Entrez Gene)
Chr12 NP_571784 (RefSeq)
NM_131709 (RefSeq)
frog, western clawed zeb1 548525 (Entrez Gene)
Chr6 NP_001015808 (RefSeq)
NM_001015808 (RefSeq)
macaque, rhesus ZEB1 701157 (Entrez Gene)
Chr9 XP_028681976 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory