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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
99735

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:99735

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:99735
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003779actin bindingCfl1IMPRatRGD:724709|PMID:12566455
Molecular FunctionGO:0051015actin filament bindingCFL1IDAHumanPMID:11812157
Molecular FunctionGO:0051015actin filament bindingCfl1IDAMouseMGI:MGI:5784994|PMID:11809832
Molecular FunctionGO:0051015actin filament bindingCfl1IDARatRGD:11570417|PMID:24740405
Molecular FunctionGO:1902936phosphatidylinositol bisphosphate bindingCfl1IPICHEBI:18348RatRGD:11041716|PMID:19029335
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P63104HumanPMID:12361576
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P63104HumanPMID:15161933
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P27958:PRO_0000037566HumanPMID:15846844
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P60709HumanPMID:16189514
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P63261HumanPMID:16189514
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P54253HumanPMID:16713569
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:O14939HumanPMID:17853892
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P53667HumanPMID:17853892
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:Q13393HumanPMID:17853892
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P53667HumanPMID:19424295
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:Q8WYL5HumanPMID:21525957
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P60709HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:P63261HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:Q1KLZ0HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingCFL1IPIUniProtKB:Q549N0HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingCfl1IPIRGD:2192RatRGD:10053669|PMID:24195677
Molecular FunctionGO:0005515protein bindingCfl1IPIRGD:1311323RatRGD:11570554|PMID:23765104
Molecular FunctionGO:0005515protein bindingCfl1IPIUniProtKB:Q60598RatRGD:8553677|PMID:19704022
Molecular FunctionGO:0005515protein bindingCfl1IPIUniProtKB:Q66HL2RatRGD:8553677|PMID:19704022
Molecular FunctionGO:0005515protein bindingCfl1IPIUniProtKB:P54686RatRGD:8553986|PMID:20668166
Molecular FunctionGO:0019903protein phosphatase bindingCfl1IPIRGD:1351799RatRGD:11568705|PMID:26324884
Cellular ComponentGO:0031252cell leading edgeCfl1IDARatRGD:2306210|PMID:15252126
Cellular ComponentGO:0005911cell-cell junctionCfl1IDAMouseMGI:MGI:5544872|PMID:23793062
Cellular ComponentGO:0090732cofilin-actin rodCfl1IDARatRGD:11570414|PMID:24760020
Cellular ComponentGO:0030864cortical actin cytoskeletonCfl1IDAMouseMGI:MGI:3047055|PMID:15004221
Cellular ComponentGO:0030864cortical actin cytoskeletonCfl1IDAMouseMGI:MGI:3575233|PMID:15548599
Cellular ComponentGO:0005737cytoplasmCFL1IDAHumanPMID:25556234
Cellular ComponentGO:0005737cytoplasmCfl1IDAMouseMGI:MGI:3575233|PMID:15548599
Cellular ComponentGO:0005737cytoplasmCfl1IDARatRGD:2306210|PMID:15252126
Cellular ComponentGO:0043197dendritic spineCfl1IDARatRGD:11570414|PMID:24760020
Cellular ComponentGO:0070062extracellular exosomeCFL1IDAHumanPMID:19199708
Cellular ComponentGO:0070062extracellular exosomeCFL1IDAHumanPMID:20458337
Cellular ComponentGO:0070062extracellular exosomeCFL1IDAHumanPMID:23376485
Cellular ComponentGO:0070062extracellular exosomeCFL1IDAHumanPMID:23533145
Cellular ComponentGO:0031012extracellular matrixCFL1IDAHumanPMID:23979707
Cellular ComponentGO:0005615extracellular spaceCFL1IDAHumanPMID:23580065
Cellular ComponentGO:0005615extracellular spaceCfl1IDAMouseMGI:MGI:5640941|PMID:24006456
Cellular ComponentGO:0030175filopodiumCfl1IDARatRGD:11570532|PMID:24515839
Cellular ComponentGO:0005925focal adhesionCFL1IDAHumanPMID:21423176
Cellular ComponentGO:0030426growth coneCfl1IDARatRGD:11570532|PMID:24515839
Cellular ComponentGO:0030027lamellipodiumCfl1IDARatRGD:2306210|PMID:15252126
Cellular ComponentGO:0016020membraneCFL1IDAHumanPMID:19946888
Cellular ComponentGO:0031966mitochondrial membraneCfl1IDARatRGD:11568691|PMID:27642592
Cellular ComponentGO:0043005neuron projectionCfl1IDARatRGD:11570414|PMID:24760020
Cellular ComponentGO:0043025neuronal cell bodyCfl1IDARatRGD:11570532|PMID:24515839
Cellular ComponentGO:0097060synaptic membraneCfl1IDARatRGD:12738361|PMID:25708984
Cellular ComponentGO:0031982vesicleCFL1IDAHumanPMID:19190083
Biological ProcessGO:0030042actin filament depolymerizationCFL1IDAHumanPMID:11812157
Biological ProcessGO:0030042actin filament depolymerizationCfl1IDAMouseMGI:MGI:5784994|PMID:11809832
Biological ProcessGO:0030043actin filament fragmentationCfl1IDAMouseMGI:MGI:5784994|PMID:11809832
Biological ProcessGO:0007015actin filament organizationCfl1IMPMGI:MGI:3574399MouseMGI:MGI:3526001|PMID:15606898
Biological ProcessGO:0030030cell projection organizationCfl1IDARatRGD:8554187|PMID:16286931
Biological ProcessGO:0071364cellular response to epidermal growth factor stimulusCfl1IMPRatRGD:11570555|PMID:23704350
Biological ProcessGO:0070301cellular response to hydrogen peroxideCfl1IDARatRGD:11570554|PMID:23765104
Biological ProcessGO:1990314cellular response to insulin-like growth factor stimulusCfl1IDARatRGD:10053669|PMID:24195677
Biological ProcessGO:0071347cellular response to interleukin-1Cfl1IDARatRGD:11570414|PMID:24760020
Biological ProcessGO:0071354cellular response to interleukin-6Cfl1IDARatRGD:11570414|PMID:24760020
Biological ProcessGO:0071356cellular response to tumor necrosis factorCfl1IDARatRGD:11570414|PMID:24760020
Biological ProcessGO:0007010cytoskeleton organizationCFL1IMPHumanPMID:21834987
Biological ProcessGO:0030010establishment of cell polarityCfl1IMPMGI:MGI:3574399MouseMGI:MGI:3526001|PMID:15606898
Biological ProcessGO:0000281mitotic cytokinesisCfl1IMPMouseMGI:MGI:3575233|PMID:15548599
Biological ProcessGO:0006928movement of cell or subcellular componentCfl1IMPMouseMGI:MGI:3575233|PMID:15548599
Biological ProcessGO:0032232negative regulation of actin filament bundle assemblyCfl1IMPRatRGD:11570550|PMID:24093776
Biological ProcessGO:0030835negative regulation of actin filament depolymerizationCfl1IMPRatRGD:2306210|PMID:15252126
Biological ProcessGO:0007162negative regulation of cell adhesionCfl1IMPRatRGD:11074527|PMID:26169356
Biological ProcessGO:2000146negative regulation of cell motilityCfl1IMPRatRGD:11570550|PMID:24093776
Biological ProcessGO:0045792negative regulation of cell sizeCfl1IDARatRGD:8554187|PMID:16286931
Biological ProcessGO:1902951negative regulation of dendritic spine maintenanceCfl1IMPRatRGD:11570553|PMID:23974706
Biological ProcessGO:0010593negative regulation of lamellipodium assemblyCfl1IMPRatRGD:11570550|PMID:24093776
Biological ProcessGO:1905875negative regulation of postsynaptic density organizationCfl1IMPRatRGD:11074527|PMID:26169356
Biological ProcessGO:0051511negative regulation of unidimensional cell growthCfl1IMPRatRGD:11570550|PMID:24093776
Biological ProcessGO:0001755neural crest cell migrationCfl1IMPMGI:MGI:3574399MouseMGI:MGI:3530675|PMID:15649475
Biological ProcessGO:0001842neural fold formationCfl1IMPMGI:MGI:3574399MouseMGI:MGI:3530675|PMID:15649475
Biological ProcessGO:0044794positive regulation by host of viral processCFL1IMPHumanPMID:25556234
Biological ProcessGO:0030836positive regulation of actin filament depolymerizationCfl1IMPMouseMGI:MGI:3575233|PMID:15548599
Biological ProcessGO:0030836positive regulation of actin filament depolymerizationCfl1IDAMouseMGI:MGI:5554982|PMID:23921380
Biological ProcessGO:2000814positive regulation of barbed-end actin filament cappingCfl1IMPRatRGD:11570555|PMID:23704350
Biological ProcessGO:0030307positive regulation of cell growthCfl1IMPRatRGD:11570550|PMID:24093776
Biological ProcessGO:2000147positive regulation of cell motilityCfl1IMPRatRGD:9590192|PMID:24214978
Biological ProcessGO:0060999positive regulation of dendritic spine developmentCfl1IMPRatRGD:11570400|PMID:25723479
Biological ProcessGO:2000784positive regulation of establishment of cell polarity regulating cell shapeCfl1IMPRatRGD:11074527|PMID:26169356
Biological ProcessGO:0051894positive regulation of focal adhesion assemblyCfl1IMPRatRGD:11570550|PMID:24093776
Biological ProcessGO:0010592positive regulation of lamellipodium assemblyCfl1IMPRatRGD:2306210|PMID:15252126
Biological ProcessGO:1904783positive regulation of NMDA glutamate receptor activityCfl1IMPRatRGD:11570552|PMID:24089484
Biological ProcessGO:1905873positive regulation of protein localization to cell leading edgeCfl1IMPRatRGD:11568705|PMID:26324884
Biological ProcessGO:0045862positive regulation of proteolysisCfl1IMPRatRGD:11570550|PMID:24093776
Biological ProcessGO:0031915positive regulation of synaptic plasticityCfl1IMPRatRGD:11570400|PMID:25723479
Biological ProcessGO:0006606protein import into nucleusCfl1IMPRatRGD:724709|PMID:12566455
Biological ProcessGO:0006468protein phosphorylationCfl1IDAMouseMGI:MGI:3692803|PMID:17018287
Biological ProcessGO:0022604regulation of cell morphogenesisCFL1IMPHumanPMID:21834987
Biological ProcessGO:0061001regulation of dendritic spine morphogenesisCFL1IMPHumanPMID:24464040
Biological ProcessGO:0043200response to amino acidCfl1IDAMouseMGI:MGI:3692803|PMID:17018287

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory